Table 2.
Hemodynamic data in conscious intact and RK-NX rats before and after amlodipine
| Group (n) | Average No. of Recordings per Rat | MAP, mm Hg | Left RBF, ml/min | Conductance, ml/min per mm Hg |
|---|---|---|---|---|
| Intact (n=10) | 1.9±0.15 | 102.6±2.2 | 7.00±0.5 | 0.07±0.01 |
| Intact plus amlodipine (n=10) | 2.8±0.25 | 94.2±2.2a | 7.6±3.3 | 0.08±0.01 |
| RK-NX (n=15) | 3.7±0.19 | 126.4±3.2b | 12.9±1.5b | 0.1±0.01 |
| RK-NX plus amlodipine (n=15) | 2.4±0.27 | 105.8±2.0a | 13.6±1.8 | 0.13±0.02a |
Results are shown as mean±SEM.
a
P<0.01 maximum after amlodipine versus respective intact or RK-NX at baseline; P values >0.01 were considered nonsignificant (see statistical analysis methods for explanation).
b
P<0.01 maximum versus intact.