Table 2.
CFHR Gene Variations in C3 Glomerulopathy affect FHR Plasma Levels, but not Factor H and FHL1 plasma levels
Variable | Intact | Affected | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
FHL1 | Factor H | FHR3 | FHR1 | FHR 4 | FHR2 | FHR5 | |||||
FHR3::FHR4 | 100 | 100 | 0 | FHR3::FHR4 | 0 | 50 | 100 Mutated | 100 | |||
FHR1::FHR5 | 100 | 100 | 100 | 50 | FHR1::FHR5 | 50 | 50 | 50 | |||
FHR1::FHR5 | 100 | 100 | 50 | 0 | FHR1::FHR5 | 50 | 50 | 50 | |||
FHR2::FHR5 | 100 | 100 | 100 | 100 | 100 | 50 | FHR2::FHR5 | 50 | |||
FHR1::FHR1 | 100 | 100 | 100 | 50 | FHR1::FHR1 | 100 | 100 | 100 | |||
FHR1::FHR1 | 100 | 100 | 100 | 50 | FHR1::FHR1 | 100 | 100 | 100 | |||
FHR5::FHR5 | 100 | 100 | 50 | 50 | 100 | 100 | FHR5::FHR5 | 50 | |||
FHR3::FHR1 | 100 | 100 | 100 | FHR3::FHR1 | 100 | 100 | 100 | 100 | |||
FHR5::FHR2 | 100 | 100 | 100 | 100 | 100 | 100 | FHR5::FHR2 | 100 |
Numerical data presented as %.