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. Author manuscript; available in PMC: 2020 Feb 6.
Published in final edited form as: Expert Rev Clin Immunol. 2019 Apr 22;15(6):639–656. doi: 10.1080/1744666X.2019.1596800

Table 4.

Triggers of Mast Cells Without Degranulation

Triggers Mediator
 Peptides
 CRH VEGF
 SCF IL-6
Cytokines
 IL-1β IL-6
 IL-33 IL-31
 IL-33 CX CL8 (IL-8)
 IL-33 + SP TNF, VEGF
Heavy metals
 Aluminum
 Cadmium
 Mercury
Herbicides
 Atrazine
 Glyphosate
Pathogens
 Borrelia (Lyme disease)* TNF
 LPS TNF
 Poly (I:C) (viruses) IL-6, TNF
 Sporothrix (mold)* IL-6, TNF
*

Mycotoxins