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. 2004 Oct 18;2004(4):CD002924. doi: 10.1002/14651858.CD002924.pub2

Comparison 1. Care pathway care versus standard care.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Death by the end of follow‐up 3 783 Odds Ratio (M‐H, Random, 95% CI) 0.88 [0.49, 1.57]
1.1 Randomised studies 1 152 Odds Ratio (M‐H, Random, 95% CI) 1.77 [0.61, 5.14]
1.2 Non‐randomised studies 2 631 Odds Ratio (M‐H, Random, 95% CI) 0.69 [0.44, 1.07]
2 Death in hospital 4 1099 Odds Ratio (M‐H, Random, 95% CI) 0.86 [0.59, 1.25]
2.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
2.2 Non‐randomised studies 4 1099 Odds Ratio (M‐H, Random, 95% CI) 0.86 [0.59, 1.25]
3 Dependency at discharge (mean Functional Indepedence Measure) 2 667 Mean Difference (IV, Random, 95% CI) ‐3.77 [‐7.31, ‐0.23]
3.1 Randomised studies 1 121 Mean Difference (IV, Random, 95% CI) ‐4.90 [‐14.58, 4.78]
3.2 Non‐randomised studies 1 546 Mean Difference (IV, Random, 95% CI) ‐3.60 [‐7.40, 0.20]
4 Dead or dependent (modified Rankin Score >2) by the end of follow‐up 1 152 Odds Ratio (M‐H, Random, 95% CI) 1.36 [0.68, 2.72]
4.1 Randomised studies 1 152 Odds Ratio (M‐H, Random, 95% CI) 1.36 [0.68, 2.72]
4.2 Non‐randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
5 Discharged to Institutional care 7 1613 Odds Ratio (M‐H, Random, 95% CI) 0.79 [0.55, 1.13]
5.1 Randomised studies 1 152 Odds Ratio (M‐H, Random, 95% CI) 0.57 [0.24, 1.35]
5.2 Non‐randomised studies 6 1461 Odds Ratio (M‐H, Random, 95% CI) 0.82 [0.55, 1.23]
6 Death in hospital or discharged to institutional care 3 842 Odds Ratio (M‐H, Random, 95% CI) 0.80 [0.61, 1.05]
6.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
6.2 Non‐randomised studies 3 842 Odds Ratio (M‐H, Random, 95% CI) 0.80 [0.61, 1.05]
7 Discharged to home 7 1613 Odds Ratio (M‐H, Random, 95% CI) 1.18 [0.88, 1.59]
7.1 Randomised studies 1 152 Odds Ratio (M‐H, Random, 95% CI) 1.14 [0.56, 2.32]
7.2 Non‐randomised studies 6 1461 Odds Ratio (M‐H, Random, 95% CI) 1.20 [0.84, 1.70]
8 Complication: Pneumonia 4 797 Odds Ratio (M‐H, Random, 95% CI) 0.89 [0.53, 1.50]
8.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
8.2 Non‐randomised studies 4 797 Odds Ratio (M‐H, Random, 95% CI) 0.89 [0.53, 1.50]
9 Complication: Urinary tract infection 6 1283 Odds Ratio (M‐H, Random, 95% CI) 0.51 [0.34, 0.79]
9.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
9.2 Non‐randomised studies 6 1283 Odds Ratio (M‐H, Random, 95% CI) 0.51 [0.34, 0.79]
10 Complication: Deep vein thrombosis 2 490 Odds Ratio (M‐H, Random, 95% CI) 1.92 [0.22, 16.70]
10.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
10.2 Non‐randomised studies 2 490 Odds Ratio (M‐H, Random, 95% CI) 1.92 [0.22, 16.70]
11 Complication: Pressure sores 2 401 Odds Ratio (M‐H, Random, 95% CI) 0.55 [0.09, 3.45]
11.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
11.2 Non‐randomised studies 2 401 Odds Ratio (M‐H, Random, 95% CI) 0.55 [0.09, 3.45]
12 Complication: Dehydration 1 50 Odds Ratio (M‐H, Random, 95% CI) 0.06 [0.00, 1.11]
12.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
12.2 Non‐randomised studies 1 50 Odds Ratio (M‐H, Random, 95% CI) 0.06 [0.00, 1.11]
13 Complication: Fluid and electrolyte imbalance 1 50 Odds Ratio (M‐H, Random, 95% CI) 0.48 [0.04, 5.65]
13.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
13.2 Non‐randomised studies 1 50 Odds Ratio (M‐H, Random, 95% CI) 0.48 [0.04, 5.65]
14 Complication: Fever (all causes) 1 351 Odds Ratio (M‐H, Random, 95% CI) 0.81 [0.50, 1.32]
14.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
14.2 Non‐randomised studies 1 351 Odds Ratio (M‐H, Random, 95% CI) 0.81 [0.50, 1.32]
15 Complication: Seizures 2 401 Odds Ratio (M‐H, Random, 95% CI) 0.85 [0.30, 2.42]
15.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
15.2 Non‐randomised studies 2 401 Odds Ratio (M‐H, Random, 95% CI) 0.85 [0.30, 2.42]
16 Complication: Falls or fractures 2 401 Odds Ratio (M‐H, Random, 95% CI) 0.88 [0.20, 3.87]
16.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
16.2 Non‐randomised studies 2 401 Odds Ratio (M‐H, Random, 95% CI) 0.88 [0.20, 3.87]
17 Complication: Constipation 1 351 Odds Ratio (M‐H, Random, 95% CI) 0.72 [0.39, 1.31]
17.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
17.2 Non‐randomised studies 1 351 Odds Ratio (M‐H, Random, 95% CI) 0.72 [0.39, 1.31]
18 Complication: Myocardial infarction 1 139 Odds Ratio (M‐H, Random, 95% CI) 1.56 [0.06, 39.39]
18.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
18.2 Non‐randomised studies 1 139 Odds Ratio (M‐H, Random, 95% CI) 1.56 [0.06, 39.39]
19 Investigation: First or second computed tomography brain scan 4 1315 Odds Ratio (M‐H, Random, 95% CI) 2.42 [1.12, 5.25]
19.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
19.2 Non‐randomised studies 4 1315 Odds Ratio (M‐H, Random, 95% CI) 2.42 [1.12, 5.25]
20 Investigation: Computed tomography brain scan within 24 hours 2 491 Odds Ratio (M‐H, Random, 95% CI) 2.12 [1.33, 3.38]
20.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
20.2 Non‐randomised studies 2 491 Odds Ratio (M‐H, Random, 95% CI) 2.12 [1.33, 3.38]
21 Investigation: Carotid duplex study 3 766 Odds Ratio (M‐H, Random, 95% CI) 1.79 [0.76, 4.20]
21.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
21.2 Non‐randomised studies 3 766 Odds Ratio (M‐H, Random, 95% CI) 1.79 [0.76, 4.20]
22 Investigation: Echocardiography 2 491 Odds Ratio (M‐H, Random, 95% CI) 2.08 [0.94, 4.58]
22.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
22.2 Non‐randomised studies 2 491 Odds Ratio (M‐H, Random, 95% CI) 2.08 [0.94, 4.58]
23 Investigation: Electrocardiography 3 1035 Odds Ratio (M‐H, Random, 95% CI) 0.92 [0.45, 1.89]
23.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
23.2 Non‐randomised studies 3 1035 Odds Ratio (M‐H, Random, 95% CI) 0.92 [0.45, 1.89]
24 Investigation: Chest x‐ray 2 491 Odds Ratio (M‐H, Random, 95% CI) 0.55 [0.23, 1.31]
24.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
24.2 Non‐randomised studies 2 491 Odds Ratio (M‐H, Random, 95% CI) 0.55 [0.23, 1.31]
25 Investigation: Cerebral angiography (catheter or MR angiography) 2 491 Odds Ratio (M‐H, Random, 95% CI) 3.55 [0.24, 51.91]
25.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
25.2 Non‐randomised studies 2 491 Odds Ratio (M‐H, Random, 95% CI) 3.55 [0.24, 51.91]
26 Medication: Use of heparin (subcutaneous or intravenous) in acute period 2 491 Odds Ratio (M‐H, Random, 95% CI) 1.23 [0.25, 6.01]
26.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
26.2 Non‐randomised studies 2 491 Odds Ratio (M‐H, Random, 95% CI) 1.23 [0.25, 6.01]
27 Medication: Use of new antihypertensive therapy in the acute period 2 491 Odds Ratio (M‐H, Random, 95% CI) 0.15 [0.00, 4.65]
27.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
27.2 Non‐randomised studies 2 491 Odds Ratio (M‐H, Random, 95% CI) 0.15 [0.00, 4.65]
28 Medication: Use of intravenous fluids 1 351 Odds Ratio (M‐H, Random, 95% CI) 0.96 [0.62, 1.47]
28.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
28.2 Non‐randomised studies 1 351 Odds Ratio (M‐H, Random, 95% CI) 0.96 [0.62, 1.47]
29 Procedure: Urinary catheterisation for patients with incontinence 1 155 Odds Ratio (M‐H, Random, 95% CI) 0.78 [0.41, 1.48]
29.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
29.2 Non‐randomised studies 1 155 Odds Ratio (M‐H, Random, 95% CI) 0.78 [0.41, 1.48]
30 Procedure: Use of thrombo‐embolism deterrent stockings 2 491 Odds Ratio (M‐H, Random, 95% CI) 1.46 [0.31, 6.94]
30.1 Randomised studies (no data) 0 0 Odds Ratio (M‐H, Random, 95% CI) 0.0 [0.0, 0.0]
30.2 Non‐randomised studies 2 491 Odds Ratio (M‐H, Random, 95% CI) 1.46 [0.31, 6.94]
31 Patient satisfaction 1 121 Mean Difference (IV, Random, 95% CI) ‐1.10 [‐1.91, ‐0.29]
31.1 Randomised studies 1 121 Mean Difference (IV, Random, 95% CI) ‐1.10 [‐1.91, ‐0.29]
31.2 Non‐randomised studies (no data) 0 0 Mean Difference (IV, Random, 95% CI) 0.0 [0.0, 0.0]
32 Duration of hospital stay 6 1915 Mean Difference (IV, Random, 95% CI) ‐1.39 [‐2.80, 0.02]
32.1 Randomised studies 2 273 Mean Difference (IV, Random, 95% CI) 3.99 [‐0.29, 8.27]
32.2 Non‐randomised studies 4 1642 Mean Difference (IV, Random, 95% CI) ‐1.89 [‐2.95, ‐0.82]
33 Readmission or emergency department attendance after discharge 2 110 Odds Ratio (M‐H, Random, 95% CI) 0.11 [0.03, 0.39]
33.1 Randomised studies 1 60 Odds Ratio (M‐H, Random, 95% CI) 0.15 [0.04, 0.59]
33.2 Non‐randomised studies 1 50 Odds Ratio (M‐H, Random, 95% CI) 0.03 [0.00, 0.63]