Figure 3. The effect of TMF on learning and memory behavior performance was investigated by Morris water maze test. (A) The tracking for the last training day by the SMART program. (B) The tracking for the trial test. (C) Escape latency time for 5 days. (D) Escape latency time on the last day. (E) Time spent in target quadrant during the probe trial. (F) Swimming speed. The data are the mean ± SEM from three independent experiments (***p<0.001 compared with the control group, ^##p<0.01, ^###p<0.001 compared with the DEX group, ^$p<0.05 compared with pioglitazone treatment in the DEX administration group).