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. 2020 Jan 30;13:585. doi: 10.3389/fncel.2019.00585

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Copyright © 2020 Zeng, Bai, Jiang, Zhu, Fu, He, Zhu, Chen, Li, Fu and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Treatment with liraglutide decreased brain atrophy, enhanced axonal repair, and accelerated remyelination after HI injury. (A) General observation of rat brains from each group at day 7 post HI injury. Scale bar = 1 mm. (B) Representative images of immunohistochemical staining for microtubule-associated protein 2 (MAP-2) and myelin basic protein (MBP). Scale bar = 25 μm, 50 μm. Protein expression level (C) and quantification data of MAP-2 (D) and MBP (E) at day 7 post HI injury. **P < 0.01 and ***P < 0.001 vs. the sham group. ^#P < 0.05 vs. the HI group. Values are presented as mean ± SEM. n = 3.