Figure 1.

Upregulation of STAT3 expression in cirrhosis patient liver. Relative gene expression of (A) STAT3, (B) COL1A1 (collagen type I alpha 1), (C) ACTA2 (alpha smooth muscle actin), and (D) correlative analysis of STAT3 and collagen‐I expression of cirrhotic liver tissues vs healthy controls. Data are presented as mean ± SEM; control (n = 8) and cirrhosis (n = 13). *P < .05, **P < .01 denotes significance. r denotes Spearman's coefficient and P denotes two‐tailed P value calculated using non‐parametric Spearman's correlative analysis with Gaussian approximation