| 1 Global state: 1a. No substantial improvement (defined as slight improvement or worse) |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
0.89 [0.44, 1.81] |
| 2 Global state: 2. Severely ill or worse |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
1.0 [0.43, 2.30] |
| 3 Global state: 3. Use of additional sedatives |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
2.0 [0.58, 6.85] |
| 4 Mental state |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 4.1 emotional lability |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
0.14 [0.01, 2.59] |
| 4.2 euphoria |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
0.33 [0.04, 2.93] |
| 5 Leaving the study early |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 5.1 any reason |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
0.5 [0.05, 5.06] |
| 5.2 due to deterioration |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
1.0 [0.07, 14.85] |
| 6 Behaviour: Agitation |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
0.11 [0.01, 1.93] |
| 7 Adverse events: 1. Extrapyramidal |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 7.1 non‐specific ‐ use of antiparkinson drugs |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
1.0 [0.16, 6.38] |
| 7.2 specific ‐ akathisia |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
0.67 [0.13, 3.55] |
| 7.3 specific ‐ dyskinesia, oral |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
3.00 [0.34, 26.33] |
| 7.4 specific ‐ dystonic reaction |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
5.0 [0.26, 97.70] |
| 7.5 specific ‐ rigidity |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
1.33 [0.34, 5.17] |
| 7.6 specific ‐ salivation, excessive |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
2.0 [0.41, 9.65] |
| 7.7 specific ‐ tremor |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
1.0 [0.29, 3.43] |
| 8 Adverse events: 2. Miscellaneous |
1 |
|
Risk Ratio (M‐H, Random, 95% CI) |
Subtotals only |
| 8.1 dry mouth |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
3.00 [0.13, 69.31] |
| 8.2 headache |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
1.0 [0.16, 6.38] |
| 8.3 nausea |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
3.00 [0.13, 69.31] |
| 8.4 perspiration, excessive |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
1.0 [0.07, 14.85] |
| 8.5 rash |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
0.33 [0.01, 7.70] |
| 8.6 urinary frequency |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
3.00 [0.13, 69.31] |
| 8.7 weakness/lethargy |
1 |
38 |
Risk Ratio (M‐H, Random, 95% CI) |
3.00 [0.13, 69.31] |
