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. 2004 Jan 26;2004(1):CD003545. doi: 10.1002/14651858.CD003545.pub2

Angus 1969.

Methods Allocation: randomly assigned (according to a code prepared in advance and held by the pharmacist). 
 Blindness: double. 
 Design: 2 parallel group, single centre. 
 Duration: 6 months (results in 6 weeks). 
 Analysis: intention‐to‐treat. 
 Country: USA.
Participants Diagnosis: Scheneider criteria. 
 N=42. 
 Age: range 17‐57 years, mean 38.5 years. 
 Sex: M 14, F 28. 
 Setting: hospital.
Interventions 1.Trifluoperazine: range 7.5‐45 mg/day. N=22. 
 2.SK&F 14,336: range 100‐600 mg/day. N=20.
Outcomes Global state: (global ratings of improvement). 
 Side‐effects. 
 Use of antiparkinson agents.
Unable to use ‐ 
 Mental state: (BPRS ‐ no data). 
 Behaviour: (NOSIE ‐ no data). 
 Leaving the study early ‐ no usable data. 
 Global state: (degree of severity of the illness scale ‐ no data).
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ Adequate