Angus 1969.
Methods | Allocation: randomly assigned (according to a code prepared in advance and held by the pharmacist). Blindness: double. Design: 2 parallel group, single centre. Duration: 6 months (results in 6 weeks). Analysis: intention‐to‐treat. Country: USA. | |
Participants | Diagnosis: Scheneider criteria. N=42. Age: range 17‐57 years, mean 38.5 years. Sex: M 14, F 28. Setting: hospital. | |
Interventions | 1.Trifluoperazine: range 7.5‐45 mg/day. N=22. 2.SK&F 14,336: range 100‐600 mg/day. N=20. | |
Outcomes | Global state: (global ratings of improvement).
Side‐effects.
Use of antiparkinson agents. Unable to use ‐ Mental state: (BPRS ‐ no data). Behaviour: (NOSIE ‐ no data). Leaving the study early ‐ no usable data. Global state: (degree of severity of the illness scale ‐ no data). |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Low risk | A ‐ Adequate |