Bankier 1968.
Methods | Allocation: randomly assigned, no further information. Blindness: double (identical capsules and IM preparations). Design: 2 parallel groups arranged into 8 subgroups with 8 to 10 patients in each, single centre. Duration: 6 months (phase III and VI) preceded by phase II (2 weeks washout) plus phase I (2 weeks assessment period). Analysis: intention‐to‐treat. Country: Canada. | |
Participants | Diagnosis: schizophrenia, no further details. N=70. Age: mean 47.8 years. Sex: M 48, F24 (report 2 more patients)#. Setting: hospital. History: chronic (mean 17.5 years of hospitalisation). | |
Interventions | 1. Trifluoperazine: dose no data, only the equivalence between both drugs. N=35. 2. Fluphenazine enanthate (Prolixin): dose no data, only the equivalence between both drugs. N=35. | |
Outcomes | Side effects.
Leaving the study early. Mental state: (psychological tests; Bender‐Gestalt Score; Hooper VOT scores, MSRPP ratings ‐ no SD). Behaviour: (daily ward reports ‐ nursing staff). Laboratory tests. |
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Notes | # report 48 male plus 24 female=72 patients. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |