Bishop 1966.
Methods | Allocation: "prearranged randomised procedure", no further details. Blindeness: double, (identical capsules supplied in individual bottles only with the subjects study number). Design: 2 parallel groups, two centres. Duration: 30 days. Analysis: intention‐to‐treat. Country: USA. | |
Participants | Diagnosis: schizophrenia, no further information. N=40. Age: range 18‐54 years, mean 34.3 years. Sex: M 21, F 19. Setting: hospital. History: newly admitted patients, trifluoperazine group > paranoid diagnosis. | |
Interventions | 1. Trifluoperazine: range 5‐30 mg/day. N=21. 2. Thiothixene: range 5‐30 mg/day. N=19. | |
Outcomes | Global state: (global ratings of improvement).
Side effects: (EPS). Unable to use ‐ Mental state: (BPRS, only graphs). |
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Notes | #The groups differ on sex, age and diagnostic type. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |