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. 2004 Jan 26;2004(1):CD003545. doi: 10.1002/14651858.CD003545.pub2

Bishop 1966.

Methods Allocation: "prearranged randomised procedure", no further details. 
 Blindeness: double, (identical capsules supplied in individual bottles only with the subjects study number). 
 Design: 2 parallel groups, two centres. 
 Duration: 30 days. 
 Analysis: intention‐to‐treat. 
 Country: USA.
Participants Diagnosis: schizophrenia, no further information. 
 N=40. 
 Age: range 18‐54 years, mean 34.3 years. 
 Sex: M 21, F 19. 
 Setting: hospital. 
 History: newly admitted patients, trifluoperazine group > paranoid diagnosis.
Interventions 1. Trifluoperazine: range 5‐30 mg/day. N=21. 
 2. Thiothixene: range 5‐30 mg/day. N=19.
Outcomes Global state: (global ratings of improvement). 
 Side effects: (EPS).
Unable to use ‐ 
 Mental state: (BPRS, only graphs).
Notes #The groups differ on sex, age and diagnostic type.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear