Brauzer 1971.
| Methods | Allocation: randomly assigned, no further description. Blindness: double. Design: 2 parallel groups, single centre. Duration: 1 to 3 months. Analysis: intention‐to‐treat not performed in the trial. Country: USA. | |
| Participants | Diagnosis: schizophrenia**. N=25. Age: mean 41.8 years. Sex: M 11, F 14. Setting: outpatients. History: only 20% are paranoid schizophrenics. | |
| Interventions | 1. Trifluoperazine: dose initially 5 mg/day followed by minimum 8 mg/day and maximum of 19 mg/day, then maintenance dose 13 mg/day. N=13. 2. Molindone: dose initially 10 mg/day, followed by minimum of 18 mg/day and maximum of 38 mg/day, then maintenance dose 25 mg/day. N=12. | |
| Outcomes | Use of antiparkinson agents.
Leaving the study early. Unable to use ‐ Mental state: (BPRS ‐ no SD). Side effects ‐ no data. |
|
| Notes | **Mixed diagnosis | |
| Risk of bias | ||
| Bias | Authors' judgement | Support for judgement |
| Allocation concealment? | Unclear risk | B ‐ Unclear |