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. 2004 Jan 26;2004(1):CD003545. doi: 10.1002/14651858.CD003545.pub2

Brauzer 1971.

Methods Allocation: randomly assigned, no further description. 
 Blindness: double. 
 Design: 2 parallel groups, single centre. 
 Duration: 1 to 3 months. 
 Analysis: intention‐to‐treat not performed in the trial. 
 Country: USA.
Participants Diagnosis: schizophrenia**. 
 N=25. 
 Age: mean 41.8 years. 
 Sex: M 11, F 14. 
 Setting: outpatients. 
 History: only 20% are paranoid schizophrenics.
Interventions 1. Trifluoperazine: dose initially 5 mg/day followed by minimum 8 mg/day and maximum of 19 mg/day, then maintenance dose 13 mg/day. N=13. 
 2. Molindone: dose initially 10 mg/day, followed by minimum of 18 mg/day and maximum of 38 mg/day, then maintenance dose 25 mg/day. N=12.
Outcomes Use of antiparkinson agents. 
 Leaving the study early.
Unable to use ‐ 
 Mental state: (BPRS ‐ no SD). 
 Side effects ‐ no data.
Notes **Mixed diagnosis
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear