Claghorn 1974.

Methods	Allocation: randomly assigned, no further details. Blindness: double (identical capsules). Design: 2 parallel groups, single centre. Duration: 24 weeks. Analysis: intention‐to‐treat. Country: USA.
Participants	Diagnosis: schizophrenia no further details. N=87. Age: range 22‐65 years, mean 42.5 years. Sex: M 23, F 64. Setting: outpatients. History: maintenance treatment of chronic (at least 2 years duration) adults.
Interventions	1. Trifluoperazine: range: 5‐19 mg/day (mean 12.53 mg/day). N=44. 2. Pimozide: range 2‐8 mg/day (mean 5.16 mg/day). N=43.
Outcomes	Side effects. Laboratory tests. Unable to use ‐ Mental state: (BPRS). Global state: (CGI). Behaviour: (Evaluation of Social Functioning).
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear