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. 2004 Jan 26;2004(1):CD003545. doi: 10.1002/14651858.CD003545.pub2

Gallant 1968 II.

Methods Allocation: randomly assigned, no further details. 
 Blindness: no data#. 
 Design: 2 parallel groups, single centre. 
 Duration: 1 week (preceded by minimum of 26 days washout). 
 Analysis: intention‐to‐treat. 
 Country: USA.
Participants Diagnosis: schizophrenia, no further details. 
 N=52. 
 Age: range 31‐58 years, mean 45 years. 
 Setting: hospital. 
 Sex: M 26, F 26. 
 History: chronic Illness (average length of hospitalisation 16.5 years, range 4‐28 years).
Interventions 1. Trifluoperazine: dose 20 mg/day IM (maximum). N=26. 
 2. Thiothixene: dose 20 mg/day IM (maximum). N=26.
Outcomes Global state: (global ratings of improvment). 
 Side effects: (EPS, sedation, local tissue reactions).
Mental state: (BPRS ‐ no data). 
 Behaviour: (NOSIE ‐ no data).
Notes # Blindness: no data.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear