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. 2004 Jan 26;2004(1):CD003545. doi: 10.1002/14651858.CD003545.pub2

Menon 1972.

Methods Allocation: randomly assigned, no further details. 
 Blindness: research workers blind, no further information. 
 Design: 3 parallel groups, single centre. 
 Duration: 10 weeks (preceded by 6 weeks washout). 
 Analysis: intention‐to‐treat. 
 Country: India.
Participants Diagnosis: schizophrenia (clinical criteria). 
 N=60. 
 Age: range 20‐60 years. 
 Sex: M 30, F 30. 
 Setting: hospital. 
 History: chronic, length of hospitalisation 1.5‐10 years; continuously hospitalised > 1 year. 
 Excluded: mental deficiency and physical complications.
Interventions 1. Trifluoperazine: dose 15 mg/day. N=20. 
 2. Trifluperidol: dose 1.5 mg/day. N=20. 
 3. Placebo: N=20. 
 * Antiparkinson drugs if necessary.
Outcomes Global state: (QPSS scale). 
 Behaviour: (Wings scale). 
 Side effects: (EPS, nausea and vomiting).
Unable to use ‐ 
 Laboratory tests ‐ no data.
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear