Menon 1972.
Methods | Allocation: randomly assigned, no further details. Blindness: research workers blind, no further information. Design: 3 parallel groups, single centre. Duration: 10 weeks (preceded by 6 weeks washout). Analysis: intention‐to‐treat. Country: India. | |
Participants | Diagnosis: schizophrenia (clinical criteria). N=60. Age: range 20‐60 years. Sex: M 30, F 30. Setting: hospital. History: chronic, length of hospitalisation 1.5‐10 years; continuously hospitalised > 1 year. Excluded: mental deficiency and physical complications. | |
Interventions | 1. Trifluoperazine: dose 15 mg/day. N=20. 2. Trifluperidol: dose 1.5 mg/day. N=20. 3. Placebo: N=20. * Antiparkinson drugs if necessary. | |
Outcomes | Global state: (QPSS scale).
Behaviour: (Wings scale).
Side effects: (EPS, nausea and vomiting). Unable to use ‐ Laboratory tests ‐ no data. |
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Notes | ||
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |