Rubin 1971.
Methods | Allocation: randomly assigned, no further description. Blindness: double (identical capsules). Design: 2 parallel groups. Duration: minimum 5 days, maximum 79 days. Analysis: intention‐to‐treat. Country: USA. | |
Participants | Diagnosis: *psychotic patients: paranoid schizophrenics (13); undifferentiated schizophrenia (4); Manic‐depressive (1). N=18. Age: range 26‐49 years, mean 37.5 years. Sex: only male. Setting: hospital. History: acute illness. | |
Interventions | 1. Trifluoperazine: range 6‐60 mg/day. N=8. 2. Haloperidol: range 2‐20 mg/day. N=10. 3 patients receiving TFP began group psychotherapy. | |
Outcomes | Global state: (Mental Status Schedule; discharged from hospital. Unable to use ‐ Average time of onset of Therapeutic Effect: (only patients who improved). |
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Notes | **Mixed diagnosis. | |
Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Unclear risk | B ‐ Unclear |