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. 2004 Jan 26;2004(1):CD003545. doi: 10.1002/14651858.CD003545.pub2

Rubin 1971.

Methods Allocation: randomly assigned, no further description. 
 Blindness: double (identical capsules). 
 Design: 2 parallel groups. 
 Duration: minimum 5 days, maximum 79 days. 
 Analysis: intention‐to‐treat. 
 Country: USA.
Participants Diagnosis: *psychotic patients: paranoid schizophrenics (13); undifferentiated schizophrenia (4); Manic‐depressive (1). 
 N=18. 
 Age: range 26‐49 years, mean 37.5 years. 
 Sex: only male. 
 Setting: hospital. 
 History: acute illness.
Interventions 1. Trifluoperazine: range 6‐60 mg/day. N=8. 
 2. Haloperidol: range 2‐20 mg/day. N=10. 
 3 patients receiving TFP began group psychotherapy.
Outcomes Global state: (Mental Status Schedule; discharged from hospital.
Unable to use ‐ 
 Average time of onset of Therapeutic Effect: (only patients who improved).
Notes **Mixed diagnosis.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear