*Bankier 1973.

Methods	Allocation: randomly assigned, no further details. Blindness: double (identical oral preparations, but not in IM preparation ‐ saline by a senior nurse). Design: 2 parallel groups, single centre. Duration: 16 weeks. Analysis: not clearly described in the report, (ITT)?* Country: Canada.
Participants	Diagnosis: schizophrenia, no further details. N=24. Age: mean 33.1 years. Sex: M 15, F 9. Setting: hospital. History: acutely disturbed (mean length of illness 98.5 months.
Interventions	1. Trifluoperazine: dose (mean 40 mg/day). N=13. 2. Fluspirilene: dose (mean 3.25 ml, 1 amp IM/week). N=11.
Outcomes	Leaving the study early. Side effects. Unable to use ‐ Mental state: (BPRS ‐ only graph; NOSIE ‐ no data). Laboratory tests ‐ no data. EKG ‐ no data.
Notes	*ITT unclear.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear