| Methods |
Randomized, double blind placebo‐controlled, crossover trial. Following a 2 week pre‐randomization placebo lead‐in period |
| Participants |
12 participants enrolled, 10 (9 boys, 1 girl) completed program; mean age 6yrs 3 mo, range 3 yrs old to 12.9 years old |
| Interventions |
1. B6+Mg (4 weeks) then Placebo (4 weeks)2.Placebo (4 weeks) then B6+Mg (4 weeks)Dosage: B6: 30mg/kg/day (max =1gram);Mg:10mg/kg/day (max =350mg/day) |
| Outcomes |
Performance on CARS, CGI, CPRS, OCS scales |
| Notes |
B |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Allocation concealment? |
Unclear risk |
B ‐ Unclear |
