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. 2005 Oct 19;2005(4):CD003497. doi: 10.1002/14651858.CD003497.pub2

Tolbert 1993.

Methods Randomized double‐blind placebo controlled, 
 asymmetric cross‐over trial; 10 week treatment blocks
Participants Treated participants:10 males & 5 females diagnosed using DSM‐III‐R criteria (age range, 6 to 18)
Interventions 1.B6+Mg (20 weeks) then Placebo 10 (weeks) 
 2.B6+Mg (10 weeks) then Placebo (10 weeks)then B6+Mg (10 weeks) 
 Dosage: B6: 200mg/70kg weight 
 Mg: 100mg/70kg weight
Outcomes Sensory‐motor; 
 social behaviour; affective behaviour; sensory responses; language
Notes Reported data not in useable form for analysis; Control group not randomly assigned
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear