Avorn 1983.

Methods	RCT unit of allocation: provider unit of analysis: episode of care power calculation: not done concealment of allocation: not clear follow up of professionals: done blinded assessment of outcome: done baseline measurement: done reliable primary outcome measure: done protection against contamination: done analysis appropriate: no
Participants	435 physicians in Arkansa, Vermont, New Hampshire and District of Columbia, USA treating patients for community acquired infection
Interventions	1. Printed educational materials 2. Printed educational materials + academic detailing by pharmacist 3. No intervention control
Outcomes	Professional practice: Change in rates of prescribing cephalexin (primary outcome) Changes in rate of prescribing of alternative drugs that might be substituted for target drugs Change in costs associated with changes in prescribing
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear