De Santis 1984.

Methods	RCT unit of allocation: post code region unit of analysis: prescriptions power calculation: not clear concealment of allocation: not clear follow up of professionals: not done blinded assessment of outcome: not clear baseline measurement: not clear reliable primary outcome measure: not clear protection against contamination: done analysis appropriate: no
Participants	439 GPs in 8 regions in Victoria, Australia treating patients of all ages with tonsillitis
Interventions	1. Academic detailing by pharmacist + educational materials 2. No intervention control
Outcomes	Professional practice: Change in rate prescribing recommended antibiotics for pharyngitis Patient: none
Notes	Prescribing recommendations Victoria Health Department Prescribing Guidelines
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Unclear risk	B ‐ Unclear