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. 2005 Oct 19;2005(4):CD003539. doi: 10.1002/14651858.CD003539.pub2

Hennessy 2002.

Methods CBA 
 unit of allocation: village 
 unit of analysis: nasopharyngeal swab specimen (for Streptococcus pneumoniae resistance assessment), episode of care (for antibiotic prescribing ) 
 power calculation: not done 
 baseline measurement: not done 
 characteristics for studies using second site as control: not clear 
 blinded assessment of primary outcome: not clear 
 protection against contamination: done 
 reliable primary outcome measure: not clear 
 follow up of professionals: not clear 
 analysis appropriate: no
Participants Physicians and community health aides and community residents in 13 villages in Alaska, USA treating patients for with respiratory tract infection
Interventions 1. Multi‐faceted interventions including educational meetings for health care providers and printed educational materials + educational meetings for villagers
2. No intervention control ‐ intervention extended to control villages in second year of study
Outcomes Professional practice: 
 Change in rate of prescribing of oral antibiotics
Patient: 
 Change in proportion of nasopharyngeal Streptococcus pneumoniae isolates resistant to penicillin
Notes Campaign message based upon evidence based guidelines: Principles of Judicious Antibiotic Use
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk D ‐ Not used