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. 2005 Oct 19;2005(4):CD003539. doi: 10.1002/14651858.CD003539.pub2

Macfarlane 2002.

Methods RCT 
 unit of allocation: patient 
 unit of analysis: patient 
 power calculation: done 
 concealment of allocation: not clear 
 follow up of patients: done 
 blinded assessment of outcome: done 
 baseline measurement: not applicable 
 reliable primary outcome measure: not clear 
 protection against contamination: not applicable 
 analysis appropriate: yes
Participants 212 adult patients with acute bronchitis from 3 general practices in Great Britain who were felt by the physician to desire but not require antibiotics
Interventions 1. Given standard verbal reassurance and prescription for antibiotics to use if they got worse along with leaflet outlining why antibiotics were not necessary for treatment of acute bronchitis
2. Given standard verbal reassurance and prescription for antibiotics to use if they got worse along with blank leaflet
Outcomes Professional practice: 
 None
Patient: 
 Proportion of patients who filled prescription
Reconsultation for same symptoms in next month
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Unclear risk B ‐ Unclear