Table 1.
Baseline characteristics for patients with baseline mLNSC assessment.
| All patients (n = 137) | |
|---|---|
| Mean age, years (s.d.) | 38.3 (12.9) |
| Female, n (%) | 107 (78.1) |
| Cushing’s disease status, n (%) | |
| Persistent or recurrent | 111 (81.0) |
| De novo | 26 (19.0) |
| Previous medical therapy, n (%) | 57 (41.6) |
| Mean mUFC (s.d.) | |
| nmol/24 h | 478.7 (303.6) |
| × ULN | 2.9 (1.8) |
| Mean mLNSC (s.d.) | |
| nmol/L | 10.4 (8.2) |
| × ULN | 3.3 (2.6) |
| Baseline diabetic status,* n (%) | |
| Diabetic | 54 (39.4) |
| Pre-diabetic | 23 (16.8) |
| Non-diabetic | 60 (43.8) |
| Baseline hypertension status,† n (%) | |
| Hypertensive | 98 (71.5) |
| Pre-hypertensive | 26 (19.0) |
| Normotensive | 13 (9.5) |
*Defined as follows: diabetic: receiving antidiabetic medication, or history of diabetes mellitus, or HbAlc (HbA1c) ≥6.5% or fasting plasma glucose (FPG) ≥126 mg/dL; pre-diabetic: not qualifying as diabetic and with FPG 100–126 mg/dL or HbA1c 5.7–6.5%; non-diabetic: not qualifying as diabetic or pre-diabetic. †Defined as follows: hypertensive: receiving antihypertensive medication, or systolic blood pressure (SBP) ≥140 mmHg or diastolic blood pressure (DBP) ≥90 mmHg; pre-hypertensive: SBP 120 to <140 mmHg or DBP 80 to <90 mmHg without antihypertensive medication; normotensive: not qualifying as hypertensive or pre-hypertensive (16).
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