Table 2. Centrality of hub genes in regulatory networks.

Genes	Degree	Closeness	Betweenness
FOS	50	74.83333	3080.334
TP53	45	73.5	2940.666
VEGFA	40	66	2763.408
JUN	33	68.5	1962.074
HIF1A	32	67.83333	2416.872
RB1	30	63.16667	1282.759
PTGS2	21	57	714.0516
IL8/CXCL8	18	57.16667	536.7006
OAS2	15	48.66667	439.0914
NFKBIA	11	54.25	296.5654
OAS1	10	50.58333	301.027
TNFSF10	7	42.2	30.24196
ATF3	5	47.83333	92.58305
IL1B	1	43.75	0
DDX58	1	43.75	0