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. 2019 Dec 10;20(1):59–65. doi: 10.1111/ggi.13820

Table 2.

Cox regression analysis of quartiles of energy intake per actual or standard bodyweight and all‐cause mortality

Actual BW
Events Q1 Q2 Q3 Q4 P‐value
≤24.85 24.86–29.73 29.74–34.78 ≥34.79
kcal/kg BW kcal/kg BW kcal/kg BW kcal/kg BW
HR P HR P Reference HR P
(95% CI) (95% CI) (95% CI)
Model 1 (crude) 59 3.21 0.004 1.40 0.473 1 1.91 0.141 0.051
(1.45–7.12) (0.56–3.47) (0.81–4.49)
Model 2 59 4.16 0.001 1.56 0.342 1 1.77 0.198 0.011
(1.80–9.58) (0.62–3.92) (0.74–4.21)
Model 3 50 3.87 0.002 0.94 0.905 1 1.54 0.355 0.016
(1.63–9.16) (0.32–2.76) (0.62–3.82)
Model 4§ 50 3.83 0.002 0.92 0.883 1 1.60 0.313 0.020
(1.62–9.09) (0.31–2.72) (0.64–4.00)
Standard BW
Events Q1 Q2 Q3 Q4 P‐value
≤27.77 27.78–31.44 31.45–36.42 ≥36.43
kcal/kg BW kcal/kg BW kcal/kg BW kcal/kg BW
HR P HR P Reference HR P
(95% CI) (95% CI) (95% CI)

Model 1

(crude)

59 3.23 0.004 1.21 0.689 1 1.83 0.166 0.042
(1.46–7.14) (0.48–3.06) (0.78–4.33)
Model 2 59 3.57 0.002 1.51 0.387 1 2.20 0.074 0.049
(1.60–7.97) (0.59–3.86) (0.93–5.21)
Model 3 50 3.94 0.004 1.68 0.334 1 2.22 0.116 0.046
(1.57–9.94) (0.59–4.79) (0.82–6.00)
Model 4§ 50 3.88 0.004 1.67 0.337 1 2.23 0.114 0.054
(1.53–9.79) (0.59–4.78) (0.83–6.03)

Adjusted for age, sex and body mass index.

Adjusted for age, sex, body mass index, glycated hemoglobin, systolic blood pressure, low‐density lipoprotein cholesterol, estimated glomerular filtration rate, physical activity, history of ischemic heart disease, history of stroke and history of hypoglycemia.

§

Adjusted for age, sex, body mass index, glycated hemoglobin, systolic blood pressure, low‐density lipoprotein cholesterol, estimated glomerular filtration rate, physical activity, history of ischemic heart disease, history of stroke, history of hypoglycemia and protein intake per actual bodyweight. CI, confidence interval; HR, hazard ratio; Q, quartile.