Table 3.
Odds ratios of cervical cancer in relation to screening status in the past two screening rounds, by stage and histopathological type of cancer cases
All types | Squamous cell cancer | Adenocarcinoma | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Screening status1 | No. of case sub. | No. of control sub. | OR | OR adjusted2 | No. of case sub. | No. of control sub. | OR | OR adjusted2 | No. of case sub. | No. of control sub. | OR | OR adjusted2 |
All stages (age 29+) | ||||||||||||
Unscr.–Unscr. | 1,711 | 29,670 | 4.03(3.69–4.40) | 4.14(3.79–4.52) | 1,368 | 22,099 | 5.15(4.65–5.72) | 5.28(4.75–5.87) | 207 | 5,103 | 1.61(1.30–1.98) | 1.70(1.38–2.10) |
Scr.–Unscr. | 783 | 17,716 | 2.41(2.18–2.65) | 2.40(2.18–2.65) | 537 | 12,862 | 2.60(2.31–2.93) | 2.60(2.31–2.93) | 181 | 3,480 | 1.94(1.60–2.35) | 1.95(1.61–2.37) |
Unscr.–Scr. | 502 | 16,401 | 1.62(1.46–1.81) | 1.63(1.46–1.81) | 370 | 11,854 | 1.89(1.66–2.15) | 1.89(1.66–2.16) | 101 | 3,364 | 1.10(0.87–1.39) | 1.11(0.88–1.40) |
Scr.–Scr. | 1,045 | 51,829 | Ref. | Ref. | 665 | 37,170 | Ref. | Ref. | 298 | 10,711 | Ref. | Ref. |
Stage IA (microinvasive) | ||||||||||||
Unscr.–Unscr. | 165 | 3,280 | 2.51(2.04–3.09) | 2.63(2.13–3.25) | 138 | 2,468 | 2.98(2.36–3.75) | 3.09(2.44–3.91) | 24 | 679 | 1.36(0.83–2.23) | 1.47(0.89–2.42) |
Scr.–Unscr. | 213 | 3,408 | 3.05(2.52–3.68) | 3.05(2.53–3.69) | 165 | 2,590 | 3.32(2.67–4.13) | 3.33(2.67–4.14) | 43 | 755 | 2.19(1.47–3.27) | 2.21(1.48–3.31) |
Unscr.–Scr. | 133 | 3,874 | 1.65(1.33–2.04) | 1.65(1.33–2.05) | 100 | 2,966 | 1.72(1.34–2.21) | 1.73(1.35–2.22) | 29 | 843 | 1.31(0.84–2.05) | 1.33(0.85–2.08) |
Scr.–Scr. | 249 | 11,695 | Ref. | Ref. | 182 | 9,104 | Ref. | Ref. | 64 | 2,418 | Ref. | Ref. |
Stage IB+ (frankly invasive) | ||||||||||||
Unscr.–Unscr. | 1,546 | 26,390 | 4.45(4.03–4.90) | 4.54(4.11–5.02) | 1,230 | 19,631 | 5.89(5.23–6.63) | 6.00(5.32–6.76) | 183 | 4,424 | 1.66(1.31–2.09) | 1.75(1.38–2.21) |
Scr.–Unscr. | 570 | 14,308 | 2.24(2.00–2.50) | 2.23(1.99–2.50) | 372 | 10,272 | 2.39(2.08–2.75) | 2.38(2.07–2.75) | 138 | 2,725 | 1.87(1.50–2.33) | 1.88(1.51–2.35) |
Unscr.–Scr. | 369 | 12,527 | 1.62(1.43–1.84) | 1.62(1.43–1.84) | 270 | 8,888 | 1.96(1.68–2.29) | 1.96(1.68–2.28) | 72 | 2,521 | 1.04(0.79–1.36) | 1.05(0.80–1.37) |
Scr.–Scr. | 796 | 40,134 | Ref. | Ref. | 483 | 28,066 | Ref. | Ref. | 234 | 8,293 | Ref. | Ref. |
Stage II+ (advanced) | ||||||||||||
Unscr.–Unscr. | 1,066 | 17,466 | 7.76(6.65–9.06) | 7.68(6.57–8.97) | 887 | 13,772 | 9.95(8.30–11.9) | 9.95(8.29–11.9) | 99 | 2,278 | 2.34(1.55–3.54) | 2.30(1.51–3.49) |
Scr.–Unscr. | 213 | 7,059 | 2.44(2.02–2.96) | 2.41(1.99–2.92) | 150 | 5,567 | 2.58(2.05–3.24) | 2.55(2.03–3.21) | 37 | 880 | 1.84(1.18–2.88) | 1.82(1.16–2.85) |
Unscr.–Scr. | 148 | 5,632 | 2.12(1.72–2.60) | 2.10(1.71–2.59) | 116 | 4,430 | 2.49(1.95–3.16) | 2.47(1.94–3.15) | 24 | 717 | 1.48(0.90–2.45) | 1.48(0.90–2.45) |
Scr.–Scr. | 253 | 17,161 | Ref. | Ref. | 171 | 13,512 | Ref. | Ref. | 52 | 2099 | Ref. | Ref. |
Left‐hand side of hyphen represents the previous screening round, and right‐hand side represents the most recent screening round.
Adjusted for education and age group.
Abbreviations: Scr., screened; Unscr., unscreened.