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. 2019 Dec 5;4(2):bvz003. doi: 10.1210/jendso/bvz003

Table 3.

Associations Between Urinary Log Phytoestrogen Concentrations (nmol/L) and Length of All Menstrual Cycles During Follow-Up

<26 days 26–35 days >35 days Continuous
OR 95% CI OR 95% CI β b 95% CIb
Genistein Unadjusted 1.01 0.88 1.16 Ref 1.01 0.83 1.21 -0.007 -0.033 0.020
Adjusteda 1.02 0.85 1.22 Ref 1.02 0.71 1.47 0.007 -0.003 0.040
Daidzein Unadjusted 1.00 0.88 1.15 Ref 0.98 0.81 1.18 -0.018 -0.044 0.009
Adjusteda 0.99 0.83 1.19 Ref 0.97 0.67 1.40 -0.008 -0.041 0.025
O-DMA Unadjusted 0.98 0.87 1.10 Ref 0.96 0.82 1.13 -0.020 -0.042 0.003
Adjusteda 0.96 0.82 1.11 Ref 1.01 0.75 1.35 0.0005 -0.028 0.027
Equol Unadjusted 1.03 0.85 1.25 Ref 0.99 0.75 1.30 -0.044 -0.082 -0.006
Adjusteda 1.00 0.77 1.27 Ref 1.00 0.59 1.69 -0.039 -0.086 0.009
Total Isoflavones Unadjusted 1.01 0.87 1.17 Ref 0.99 0.81 1.21 -0.016 -0.044 0.012
Adjusteda 1.02 0.87 1.20 Ref 0.91 0.66 1.27 -0.016 -0.046 0.013
Enterodiol Unadjusted 1.00 0.85 1.17 Ref 0.96 0.77 1.19 -0.029 -0.060 0.002
Adjusteda 0.98 0.81 1.19 Ref 1.01 0.69 1.48 -0.013 -0.049 0.022
Enterolactone Unadjusted 1.02 0.88 1.19 Ref 0.95 0.78 1.16 -0.034 -0.060 -0.006
Adjusteda 1.04 0.87 1.24 Ref 0.96 0.69 1.34 -0.016 -0.046 0.015
Total Lignans Unadjusted 1.03 0.87 1.21 Ref 0.94 0.75 1.17 -0.040 -0.072 -0.009
Adjusteda 1.03 0.85 1.25 Ref 0.94 0.65 1.35 -0.023 -0.056 0.011
Total Phytoestrogens Unadjusted 1.04 0.86 1.26 Ref 0.93 0.72 1.21 -0.043 -0.080 -0.007
Adjusteda 1.07 0.87 1.32 Ref 0.85 0.55 1.29 -0.042 -0.080 -0.003

Bold values indicate P <0.05.

Abbreviations: CI, confidence interval; O-DMA, O-desmethylangolensin; OR, odds ratio.

a Models adjusted for age, BMI, race, urinary creatinine, exercise (questionnaire), supplement use (yes/no), lipids, lead, cadmium, cotinine, parity conditional on gravidity, frequency of alcohol consumption, and sum of the other phytoestrogens (log).

b β and 95% CIs calculated by β/10; interpreted as: the change in cycle length (by day) per 10% increase in phytoestrogen concentration.