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. 2019 Dec 5;4(2):bvz003. doi: 10.1210/jendso/bvz003

Table 4.

Associations Between Urinary Phytoestrogens and Average Menstrual Cycle Length

<26 days 26–35 Days >35 days Continuous
OR 95% CI OR 95% CI β b 95% CIb
Genistein Unadjusted 1.07 0.93 1.23 Ref 1.08 0.88 1.32 -0.006 -0.046 0.033
Adjusteda 1.04 0.86 1.25 Ref 1.12 0.83 1.50 0.006 -0.044 0.055
Daidzein Unadjusted 1.06 0.92 1.22 Ref 1.03 0.84 1.27 -0.017 -0.057 0.022
Adjusteda 1.02 0.85 1.23 Ref 1.02 0.76 1.37 -0.008 -0.058 0.042
O-DMA Unadjusted 0.98 0.87 1.10 Ref 0.98 0.83 1.17 -0.020 -0.053 0.014
Adjusteda 0.90 0.78 1.05 Ref 1.00 0.79 1.26 0.005 -0.041 0.041
Equol Unadjusted 1.06 0.87 1.29 Ref 0.94 0.69 1.28 -0.044 -0.100 0.013
Adjusteda 0.97 0.76 1.24 Ref 0.92 0.59 1.44 -0.039 -0.110 0.030
Total Isoflavones Unadjusted 1.05 0.90 1.21 Ref 1.05 0.85 1.30 -0.017 -0.058 0.027
Adjusteda 1.03 0.88 1.22 Ref 1.03 0.80 1.33 -0.016 -0.060 0.028
Enterodiol Unadjusted 1.09 0.93 1.30 Ref 0.98 0.77 1.24 -0.028 -0.075 0.018
Adjusteda 1.08 0.89 1.32 Ref 1.02 0.76 1.36 -0.013 -0.066 0.039
Enterolactone Unadjusted 1.07 0.92 1.25 Ref 0.96 0.78 1.18 -0.034 -0.077 0.008
Adjusteda 1.07 0.89 1.28 Ref 1.02 0.79 1.31 -0.016 -0.061 0.030
Total Lignans Unadjusted 1.08 0.91 1.29 Ref 0.95 0.75 1.20 -0.040 -0.087 0.007
Adjusteda 1.08 0.88 1.31 Ref 1.00 0.76 1.32 -0.023 -0.074 0.029
Total Phytoestrogens Unadjusted 1.11 0.91 1.35 Ref 0.97 0.74 1.29 -0.043 -0.098 0.012
Adjusteda 1.11 0.89 1.37 Ref 0.95 0.69 1.30 -0.041 -0.099 0.016

Abbreviations: CI, confidence interval; O-DMA, O-desmethylangolensin; OR, odds ratio.

a Models adjusted for age, BMI, race, urinary creatinine, exercise (questionnaire), supplement use (yes/no), lipids, lead, cadmium, cotinine, parity conditional on gravidity, frequency of alcohol consumption, sum of the other phytoestrogens (log).

b β and 95% CIs calculated by β/10; interpreted as: the change in cycle length (by day) per 10% increase in phytoestrogen concentration.