Jiang 2015.

Methods	Study design: parallel‐group RCT Setting: single center trial in China Number randomised: 129 participants Unit of analysis: eyes (both eyes analyzed separately) Maximum planned (or stated) length of follow‐up: unclear Number not included in final analysis: unclear
Participants	Number of men: 33 in the intervention group and 35 in the comparator group Number of women: 29 in the intervention group and 32 in the comparator group Mean age: 60.3 years in the intervention group and 60.24 years in the comparator group Mean IOP at baseline: not reported Inclusion criteria: not reported Exclusion criteria: not reported
Interventions	Intervention (N = 62): “retinal laser photocoagulation combined with ranibizumab treatment” Comparator (N = 67): “retinal laser photocoagulation”
Outcomes	From the abstract “After the treatment, the degeneration of iris neovascularization, visual acuity, intraocular pressure, ocular fundus, and the adverse reactions were evaluated.”
Notes	Trial registration: not reported Study dates: 2012 to 2014
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	High risk	The sequence generation was not truly random (investigators assigned participants to treatment based on medical record number or a similar identifier)
Allocation concealment (selection bias)	High risk	Investigators enrolling participants could possibly foresee assignments, introducing bias
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Unclear risk of bias – insufficient information to permit judgement of low risk or high risk of bias
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Unclear risk of bias – insufficient information to permit judgement of low risk or high risk of bias
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Unclear risk of bias – insufficient information to permit judgement of low risk or high risk of bias
Selective reporting (reporting bias)	Unclear risk	Unclear risk of bias – insufficient information to permit judgement of low risk or high risk of bias
Other bias	Unclear risk	Unclear risk of bias – insufficient information to permit judgement of low risk or high risk of bias; study was not registered in a clinical trials registry and funding sources were not clearly reported