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. 2019 Aug 20;34(1):166–173. doi: 10.1111/jdv.15794

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© 2019 The Authors. Journal of the European Academy of Dermatology and Venereology published by John Wiley & Sons Ltd on behalf of European Academy of Dermatology and Venereology

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Local tolerability by visit: mean scores of signs and symptoms on the face (SAF population). Safety Population (SAF): All patients that were randomized and applied the study drug at least once. It includes all patients with facial acne/trunk acne and facial acne/without truncal acne. Local tolerability parameters including erythema, scaling, dryness and stinging/burning were evaluated at each visit on a 4‐point scale (0 = none, 1 = mild, 2 = moderate and 3 = severe) at Baseline and at Weeks 12, 20, 26, 38 and 52/ET.