Figure 3.

Pedigrees of Family 1 (A) and Family 2 (B). Arrows denote index patients harboring FBN1/FBN2 dual variants. The vertical line in the symbols (circle, female; square, male) denotes molecular genetic testing for the respective variants. Black halves (left) represent an FBN1 variant, striped halves (right) represent an FBN2 variant, and white halves represent absence of variant. The diagonal line through a symbol indicates deceased family members. The age at examination (y, years) or the year of birth and, where applicable, death is given in parentheses