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. Author manuscript; available in PMC: 2020 Dec 27.
Published in final edited form as: J Nat Prod. 2019 Dec 11;82(12):3421–3431. doi: 10.1021/acs.jnatprod.9b00787

Figure 1.

Figure 1.

In ozonolysis carbon-carbon double bonds react with ozone via a 1,3-dipolar cycloaddition. Two products are formed via the subsequent retro 1,3-diplolar cycloaddition, resulting in a ketone/aldehyde and a Criegee intermediate. The red arrows (top) and blue arrows (bottom) represent the two routes in which the molozonide can undergo the retro 1,3-diplolar cycloaddition.