Table 3. Minority variant calls made by Mykrobe using CP2 on the Global dataset.
The second column shows the number of samples where the resistance phenotype is known for the given drug. Column 4, headed "Minor R calls" shows the number of resistant calls due to a minor population resistance allele. Column 5, headed "Error rate of minor R calls", shows the percentage of minor-allele-driven resistant calls that were incorrect versus phenotype.
| Drug | Samples | Resistant
samples |
Minor R
calls |
Error rate of
minor R calls (%) |
|---|---|---|---|---|
| Ethambutol | 5501 | 1568 | 47 | 38.3 |
| Isoniazid | 5723 | 2965 | 24 | 8.33 |
| Pyrazinamide | 3599 | 1014 | 53 | 15.09 |
| Rifampicin | 5820 | 2770 | 45 | 6.67 |
| Amikacin | 1621 | 121 | 9 | 0.0 |
| Capreomycin | 1765 | 139 | 10 | 10.0 |
| Kanamycin | 1548 | 135 | 9 | 0.0 |
| Ofloxacin | 1755 | 388 | 37 | 0.0 |
| Streptomycin | 2987 | 679 | 10 | 0.0 |