Table 1.

Final EULAR/PRINTO/PRES childhood TAK classification criteria.

Criterion	Glossary
Angiographic abnormality (mandatory criterion)	Angiography (conventional, CT, or MRI) of the aorta or its main branches and pulmonary arteries showing aneurysm/dilatation, narrowing, occlusion, or thickening of the arterial wall not due to fibromuscular dysplasia or similar causes; changes usually focal or segmental
1. Pulse deficit or claudication	Lost/decreased/unequal peripheral artery pulse(s) Claudication: focal muscle pain induced by physical activity
2. Blood pressure (BP) discrepancy	Discrepancy of four limb systolic BP having a >10 mm Hg difference in any limb
3. Bruits	Audible murmurs or palpable thrills over large arteries
4. Hypertension	Systolic/diastolic BP greater than 95th centile for height
5. Acute phase reactant	Erythrocyte sedimentation rate >20 mm per first hour or CRP any value above normal (according to the local laboratory)

CT: Computer Tomography; CRP: C-reactive protein; EULAR: European League Against Rheumatism; MRI: Magnetic Resonance Imaging; PRES: Pediatric Rheumatology European Society; PRINTO: Pediatric Rheumatology International Trials Organization.