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. Author manuscript; available in PMC: 2021 Jan 1.
Published in final edited form as: Hypertension. 2019 Dec 2;75(1):131–138. doi: 10.1161/HYPERTENSIONAHA.119.13667

Figure 6. Mice lacking classical DCs have less volume and sodium retention during hypertension.

Figure 6.

(A-B) At baseline and after 7 days of Ang II infusion, WT and FLT3L−/− mice were challenged with an i.p. bolus of saline equivalent to 10% of their body weights and placed in metabolic cages for 4 hours of urine collection. The ratios of urine volumes to injected volumes and the ratio of sodium to injected sodium are shown. N=9–10 mice/group. (C) After 4 weeks of Ang II infusion, renal mRNA levels of α-ENaC, β-ENaC, γ-ENaC, NCC, NKCC2, and NHE3 were determined by real-time QPCR. N=5 mice/group. Data are mean ± SE.