Table 4. Associations between MVMnarrow lesions and pregnancy outcomes.
| MVMnarrow | Odds ratio1 | P-value | Adjusted odds ratio2 | P-value | Other significant terms in model | |||
|---|---|---|---|---|---|---|---|---|
| Occurrence in pregnancy | Yes # (%) | No # (%) | (95% CI) | (95% CI) | ||||
| Preeclampsia | Yes | 14 (4.6) | 294 (95.4) | 2.4 (1.4–4.1) | 0.002 | 2.6 (1.5–4.6) | 0.0009 | Age (P < 0.0001); Race (P < 0.0001); BMI (P < 0.0001); Smoking (P = 0.01) |
| No | 213 (2.0) | 10621 (98.0) | ||||||
| SGA | Yes | 115 (10.9) | 943 (89.1) | 10.2 (7.9–13.3) | 0.0001 | 11.5 (8.7–15.2) | 0.0001 | Age (P = 0.0003); Gestational age (P < 0.0001); BMI (P < 0.0001); Smoking (P < 0.0001) |
| No | 125 (1.2) | 10495 (98.8) | ||||||
| Prematurity | Extreme | 6 (6.0) | 94 (94.0) | 4.5 (1.9–10.6) | 0.0001 | 4.7 (2.0–11.0) | 0.0001 | Age (P = 0.02); Race (P < 0.0001); BMI (P < 0.0001); Smoking (P < 0.0001) |
| Very | 21 (6.2) | 318 (93.8) | 4.7 (2.9–7.6) | 4.7 (2.9–7.8) | ||||
| Moderate | 89 (5.2) | 1625 (94.8) | 3.9 (3.0–5.1) | 3.9 (2.9–5.2) | ||||
| Term | 133 (1.4) | 9467 (98.6) | ||||||
| Survival | Fetal death | 34 (26.0) | 97 (74.0) | 19.2 (12.7–29.1) | 0.0001 | 12.5 (7.8–19.9) | 0.0001 | Interpregnancy interval (P = 0.05); Age (P = 0.001); Gestational age (P < 0.0001); Race (P = 0.008) |
| Death before 120 days | 11 (4.7) | 225 (95.3) | 2.7 (1.4–5.0) | 1.7 (0.9–3.3) | ||||
| Survival past 120 days | 204 (1.8) | 11182 (98.2) | ||||||
| Apgar score at 1 minute | 0–3 | 20 (3.7) | 526 (96.3) | 2.2 (1.4–3.5) | 0.005 | 1.6 (1.0–2.7) | 0.10 | Interpregnancy interval (P = 0.002); Age (P = 0.008); Gestational age (P < 0.0001); BMI (P < 0.02) |
| 4–6 | 24 (1.6) | 1436 (98.4) | 1.0 (0.6–1.5) | 0.9 (0.6–1.4) | ||||
| 7–10 | 154 (1.7) | 8820 (98.3) | ||||||
| Apgar score at 5 minutes | 0–3 | 6 (4.6) | 124 (95.4) | 2.8 (1.2–6.4) | 0.0002 | 1.6 (0.6–4.1) | 0.02 | Interpregnancy interval (P = 0.02); Gestational age (P < 0.0001) |
| 4–6 | 13 (4.6) | 272 (95.4) | 2.8 (1.6–4.9) | 2.2 (1.2–3.9) | ||||
| 7–10 | 183 (1.7) | 10556 (98.3) | ||||||
1 All odds ratios were calculated as the odds of the adverse outcome relative to the odds of the best outcome where there were multiple levels of adverse outcomes.
2 Adjusted odds ratios are from logistic regression including interpregnancy interval, gestational age, maternal age, maternal race, maternal BMI and smoking. Analyses of prematurity did not include gestational age.