Table 5. Associations between MVMbroad lesions and pregnancy outcomes.
| MVMbroad | Odds ratio1 | P-value | Adjusted odds ratio2 | P-value | Other significant terms in model | |||
|---|---|---|---|---|---|---|---|---|
| Occurrence in pregnancy | Yes # (%) | No # (%) | (95% CI) | (95% CI) | ||||
| Preeclampsia | Yes | 83 (26.3) | 232 (73.7) | 1.3 (1.0–1.6) | 0.09 | 1.2 (0.9–1.6) | 0.24 | Age (P < 0.0001); Race (P < 0.0001); BMI (P < 0.0001); Smoking (P = 0.03) |
| No | 2455 (22.3) | 8576 (77.7) | ||||||
| SGA | Yes | 264 (24.3) | 820 (75.7) | 1.1 (1.0–1.3) | 0.10 | 1.2 (1.0–1.4) | 0.02 | Interpregnancy interval (P = 0.03); Age (P = 0.0002); Gestational age (P < 0.0005); BMI (P < 0.0001); Smoking (P < 0.0001) |
| No | 2388 (22.1) | 8399 (77.9) | ||||||
| Prematurity | Extreme | 69 (68.3) | 32 (31.7) | 14.0 (9.2–21.4) | 0.0001 | 14.8 (9.6–22.8) | 0.0001 | Race (P < 0.0001); BMI (P < 0.0001); Smoking (P < 0.0001) |
| Very | 272 (78.4) | 75 (21.6) | 23.6 (18.2 = 30.7) | 24.7 (18.8–32.3) | ||||
| Moderate | 1042 (59.6) | 707 (40.4) | 9.6 (8.6–10.7) | 9.8 (8.8–11.1) | ||||
| Term | 1301 (13.3) | 8473 (86.7) | ||||||
| Survival | Fetal death | 90 (62.5) | 54 (37.5) | 6.1 (4.3–8.5) | 0.0001 | 2.1 (1.4–3.1) | 0.0001 | Age (P < 0.0001); Gestational age (P < 0.0001); Race (P = 0.003) |
| Death before 120 days | 100 (41.0) | 144 (59.0) | 2.5 (1.9–3.3) | 0.7 (0.5–0.9) | ||||
| Survival past 120 days | 2494 (21.5) | 9089 (78.5) | ||||||
| Apgar score at 1 minute | 0–3 | 165 (29.6) | 392 (70.4) | 1.6 (1.3–1.9) | 0.0001 | 1.0 (0.8–1.2) | 0.53 | Interpregnancy interval (P = 0.001); Age (P = 0.007); Gestational age (P < 0.0001); BMI (P < 0.02) |
| 4–6 | 349 (23.6) | 1132 (76.4) | 1.2 (1.0–1.3) | 1.1 (0.9–1.3) | ||||
| 7–10 | 1918 (21.0) | 7214 (79.0) | ||||||
| Apgar score at 5 minutes | 0–3 | 54 (40.6) | 79 (59.4) | 2.5 (1.8–3.6) | 0.0001 | 0.7 (0.4–1.0) | 0.15 | Interpregnancy interval (P = 0.02); Gestational age (P < 0.0001) |
| 4–6 | 93 (31.9) | 199 (68.2) | 1.7 (1.3–2.2) | 0.9 (0.7–1.2) | ||||
| 7–10 | 2332 (21.4) | 8586 (78.64) | ||||||
1 All odds ratios were calculated as the odds of the adverse outcome relative to the odds of the best outcome where there were multiple levels of adverse outcomes.
2 Adjusted odds ratios are from logistic regression including interpregnancy interval, gestational age, maternal age, maternal race, maternal BMI and smoking. Analyses of prematurity did not include gestational age.