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. 2020 Feb 6;15(2):e0228664. doi: 10.1371/journal.pone.0228664

Table 6. Associations of previous spontaneous abortions and pregnancy outcomes including the presence of MVM lesions as a covariate.

Including MVMnarrow as a covariate Including MVMbroad as a covariate
Effect of previous spontaneous abortions Effect of MVM Effect of previous spontaneous abortions Effect of MVM
aOR1 P-value aOR1 P-value aOR1 P-value aOR1 P-value
Preeclampsia 1.0 (0.4–2.4) 0.98 3.5 (1.8–6.7) 0.0002 1.2 (0.5–2.7) 0.69 1.3 (0.9–1.9) 0.14
SGA 1.9 (1.3–2.9) 0.002 10.6 (7.5–15.0) 0.0001 2.2 (1.5–3.2) 0.0001 1.2 (1.0–1.5) 0.04
Prematurity 0.002 0.0001 0.0005 0.0001
    Extreme 4.1 (1.3–12.5) 3.1 (0.9–10.2) 5.7 (2.0–16.4) 14.0 (8.3–23.4)
    Very 2.9 (1.5–5.6) 4.0 (2.2–7.2) 3.1 (1.5–6.3) 29.7 (21.4–41.1)
    Moderate 1.3 (0.8–1.9) 3.5 (2.5–4.9) 1.3 (0.8–2.1) 9.9 (8.6–11.3)
Survival 0.006 0.0001 0.0008 0.008
    Fetal death 4.5 (1.8–11.3) 15.4 (8.6–27.6) 5.0 (2.2–11.6) 2.0 (1.2–3.4)
    Death before 120 days 1.1 (0.4–2.8) 1.4 (0.6–3.3) 1.1 (0.4–2.7) 0.8 (0.5–1.1)
Apgar at 1 minute 0.03 0.18 0.02 0.14
    0–3 1.6 (0.9–2.9) 1.8 (0.9–3.2) 1.8 (1.0–3.1) 1.3 (1.0–1.7)
    4–6 1.6 (1.1–2.4) 0.9 (0.5–1.6) 1.6 (1.1–2.3) 1.1 (0.9–1.3)
Apgar at 5 minutes 0.0009 0.08 0.001 0.30
0–3 5.1 (2.0–12.5) 2.2 (0.8–6.2) 5.0 (2.0–12.2) 0.7 (0.4–1.1)
4–6 0.5 (0.2–1.7) 2.0 (0.9–4.1) 0.5 (0.2–1.7) 0.9 (0.6–1.3)

1 Adjusted odds ratios are from logistic regression including interpregnancy interval, gestational age, maternal age, maternal race, maternal BMI and smoking. Analyses of prematurity did not include gestational age.