Table 4.

Change from baseline to final observation in mean Dry Eye-related Quality of Life Score

	Mean ± SD	Number of patients	p valuea
Ocular symptoms
Foreign body sensation	− 0.6 ± 1.3	468	< 0.001
Dryness	− 0.7 ± 1.2	465	< 0.001
Pain or soreness	− 0.4 ± 1.2	458	< 0.001
Fatigue	− 0.7 ± 1.2	463	< 0.001
Heaviness in the eyelids	− 0.4 ± 1.2	459	< 0.001
Redness	− 0.4 ± 1.2	459	< 0.001
Impact on daily life
Difficulty opening the eyes	− 0.4 ± 1.2	456	< 0.001
Blurred vision during activities that require sustained visual concentration	− 0.4 ± 1.2	460	< 0.001
Light sensitivity	− 0.4 ± 1.2	456	< 0.001
Symptoms worsen when reading	− 0.4 ± 1.2	458	< 0.001
Symptoms worsen when watching television or using a computer or cell phone	− 0.5 ± 1.2	455	< 0.001
Eye symptoms reduce the ability to concentrate	− 0.4 ± 1.2	454	< 0.001
Eye symptoms affect work or study	− 0.5 ± 1.2	453	< 0.001
Not feeling like going out because of eye symptoms	− 0.1 ± 0.8	456	< 0.001
Feeling depressed because of eye symptoms	− 0.4 ± 1.2	457	< 0.001

SD standard deviation

^aVersus baseline determined using paired t test