Table 3.
Comparisons of EBV DNA load, EBV DNA methylated degree and methylated type in the detection of NPC in brushing samples obtained with or without the guide of endoscopy
| Under the endoscopy | In blind brushing | P‐value | |||
|---|---|---|---|---|---|
| Number of patients | % | Number of patients | % | ||
| EBV DNA load | |||||
| Median (range) | 5144 (94‐40095) | 275 (1‐8744) | <.001[Link] | ||
| Negative | 2 | 5.3 | 17 | 44.7 | |
| Positive | 36 | 94.7 | 21 | 55.3 | |
| EBV DNA methylated degree | |||||
| Median (range) | 80.99 (36.79‐146.57) | 42.61 (0‐90.36) | <.001[Link] | ||
| Negative | 0 | 0.0 | 16 | 42.1 | |
| Positive | 38 | 100.0 | 22 | 57.9 | |
| EBV DNA methylated type | |||||
| M | 10 | 26.3 | 30 | 79.0 | |
| M > U | 28 | 73.7 | 4 | 10.5 | |
| ND | 0 | 0.0 | 4 | 10.5 | |
Abbreviations: M, methylation; ND, not detected; U, unmethylation.
P‐value from paired Wilcoxon signed—rank test