Skip to main content
. 2020 Jan 13;111(2):451–466. doi: 10.1111/cas.14279

Figure 5.

Figure 5

PLK2, PTP4A1 and RPS27L are direct target genes of both FL‐p53 and Δ1stTAD‐p53. A‐C, Genomic loci of PLK2 (chr5:57,783,671‐57,798,263) (A), PTP4A1 (chr6:64,332,522‐64,369,290) (B) and RPS27L (chr15:61,232,500‐61,238,300) (C) are shown together with the ChIP‐seq results. HCT116 p53 +/+ cells treated with or without fluorouracil (5‐FU) and serum‐deprived HCT116 p53 −/− cells were used for ChIP‐seq analysis. ChIP‐seq analyses were performed using antibodies against p53, H3K27ac, H3K4me1 and H3K4me3. The resulting sequences were mapped to the build #36 reference human genome (hg18)