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Circulating tumor cell EGFR upregulation compared to baseline value in patients with metastatic colorectal cancer treated with regorafenib (N = 50)
| Day 21 | PD | Day 21 and/or PD | |
|---|---|---|---|
| Increased ≥0.01 ng/µL, n (%) | 14 (28) | 24 (48) | 32 (64) |
| Stable/decreased, n (%) | 36 (72) | 17 (34) | 18 (36) |
| P a | .600 | .041 | .004 |
Abbreviation: PD, progressive disease.
Based on the sign test for paired data.
