Figure 6.

Endocytosis inhibitors chlorpromazine (CPZ) and imipramine (IMP) reduce the motility of SAS cells based on cell motility analysis. SAS cells were seeded in 6‐well plates (2 × 10⁴ cells/well). A‐C, After 48 h, cells were incubated without or with 10 μM CPZ or 1 μM IMP, and cell motility was recorded. Representative random moving traces of 61 cells during a 10‐min recoding period over 10 h are presented. Scale bar, 50 μm. D, Summarized data of the migrated distances within 10 h. Data are expressed as means + SD (n = 10). Student’s t test with two biological independent replicates was used to determine statistical significance; ***P < .001, compared with control