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Histopathology of subcortical heterotopia in Ccdc85c KO rats. HE stained sections of cerebrum in Ccdc85c KO rats at four weeks of age (4W) (A and B) and unaffected rats at 4W [C: wild type (WT)] or at 17W (D: WT, E: hetero). Subcortical heterotopia is broadly formed at the dorsal surface of lateral ventricles in Ccdc85c KO rats (A and B, arrowheads). No lesion is observed at the cerebral parenchyma in WT and hetero rats (C–E). Scale bar of A, 500 µm, scale bars of B–E, 100 µm.
