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. 2019 Jul 29;69(1):34–44. doi: 10.1538/expanim.19-0058

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©2020 Japanese Association for Laboratory Animal Science

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License. (CC-BY-NC-ND 4.0: http://creativecommons.org/licenses/by-nc-nd/4.0/)

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Fig. 6. — P53 is a downstream target gene of miR-181a-5p. (A) The specific binding site of miR-181a-5p on p53 was displayed, and the correlation between miR-181a-5p and p53 was assessed by dual-luciferase assay. (B) The mRNA level of p53 after miR-181a-5p inhibition was measured by quantitative real-time PCR. All data were presented as mean ± SD. ns: not significant; **P<0.01; ***P<0.001.