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. 2019 Jan 22;32(1):123–138. doi: 10.1007/s10534-018-00167-z

Table 4.

Prevalences of diabetes in  quartiles of total plasma concentrations of zinc, copper, magnesium and selenium and zinc/copper ratio in T1DM and T2DM study groups (including age-matched controls)

T1DM and age-matched controls T2DM and age-matched controls
Q1 Q2 Q3 Q4 Q1 Q2 Q3 Q4
Zinc (µM) n = 23 n = 23 n = 30 n = 16 n = 15 n = 16 n = 20 n = 20
< 11.95 11.95–12.91 12.91–14.46 ≥ 14.46 < 11.33 11.33–12.15 12.15–13.35 ≥ 13.35
% diabetes 52 48 60 25 73 75 75 80
OR (95% CI) 1 0.840 (0.285–2.873) 1.375 (0.457–4.234) 0.306 (0.090–1.204) 1 1.091 (0.264–4.490) 1.091 (0.281–5.312) 1.455 (0.357–5.822)
Copper (µM) n = 22 n = 17 n = 23 n = 26 n = 33 n = 13 n = 12 n = 12
< 13.99 13.99–14.47 14.47–16.79 ≥ 16.79 < 15.06 15.06–16.40 16.40–17.78 ≥ 17.78
% diabetes 50 29 48 64 88 69 58 67
OR (95% CI) 1 0.417 (0.111–1.541) 0.9167 (0.310–2.790) 1.800 (0.559–5.139) 1 0.310 (0.080–1.275) 0.193 (0.051–0.966)* 0.276 (0.070–1.154)
Magnesium (mM) n = 41 n = 17 n = 15 n = 19 n = 23 n = 25 n = 13 n = 9
< 0.78 0.78–0.81 0.81–0.83 ≥ 0.83 < 0.72 0.72–0.79 0.79–0.84 ≥ 0.84
% diabetes 75 35 27 21 83 84 69 44
OR (95% CI) 1 0.176 (0.058–0.628)** 0.117 (0.036–0.432)** 0.086 (0.028–0.325)*** 1 1.105 (0.288–4.220) 0.474 (0.118–1.969) 0.168 (0.031–1.064)
Selenium (µM) n = 21 n = 20 n = 19 n = 32 n = 24 n = 21 n = 19 n = 6
< 1.04 1.04–1.12 1.12–1.18 ≥ 1.18 < 1.085 1.09–1.24 1.24–1.42 ≥ 1.42
% diabetes 52 40 37 59 83 80 74 33
OR (95% CI) 1 0.606 (0.172–1.958) 0.530 (0.136–1.784) 1.329 (0.424–4.188) 1 0.850 (0.221–3.292) 0.560 (0.152–2.484) 0.100 (0.017–0.682)*
Zinc/copper n = 29 n = 23 n = 19 n = 20 n = 9 n = 35 n = 25 n = 27
< 0.734 0.734–0.893 0.893–1.070 ≥ 1.070 < 0.667 0.667–0.732 0.732–0.865 ≥ 0.865
% diabetes 62 48 37 45 56 86 80 85
OR (95% CI) 1 0.560 (0.172–1.695) 0.357 (0.104–1.233) 0.500 (0.169–1.660) 1 4.800 (1.110–19.940) 3.200 (0.732–13.560) 4.600 (1.001–22.260)

Data is presented as OR (95% CI)

Significance is indicated as *p < 0.05, **p < 0.01 and ***p < 0.001