TABLE 3.

Multivariable Associations Between Patient and Disease Factors, and Mastectomy Group Among Those with Data on Imaging Response (n = 407)

OR odds ratio, CI confidence interval, ER estrogen receptor, PR progesterone receptor, BCT breast-conserving therapy, mammo mammogram, NAC neoadjuvant chemotherapy

Factor	OR (95% CI)	p-value
Age at surgery	0.92 (0.9–0.95)	< .001
Stage		0.005
1/2	1.00
3	0.49 (0.3–0.81)
Subtype		0.014
ER−, PR−, HER2−	1.00
ER−, PR−, HER2+	0.32 (0.14–0.72)
ER/PR+, HER2−	0.46 (0.25–0.86)
ER/PR+, HER2+	0.74 (0.38–1.43)
Candidate BCT post-chemo	2.6 (1.56–4.34)	< .001
Residual palpable disease	0.58 (0.34–0.98)	0.043
Positive clinical axillary nodes	1.23 (0.53–2.84)	0.627
Persistent abnormality on any imaging (mammo and/or MRI) post NAC		0.004
No	1.00
Yes	0.39 (0.21–0.74)