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. Author manuscript; available in PMC: 2021 Feb 4.
Published in final edited form as: Cell Metab. 2019 Dec 5;31(2):339–350.e4. doi: 10.1016/j.cmet.2019.11.012

Figure 5: Keap1 mutant tumors require exogenous NEAAs in vivo.

Figure 5:

a) Relative tumor growth of subcutaneous tumors in animals receiving either -SG or AA CTL diet. b) Relative tumor growth of subcutaneous tumors in animals treated with either L-Asparaginase. c and d) Relative tumor growth of subcutaneous tumors in animals receiving -N or AA CTL diet in combination with L-asparaginase treatment. e and f) Relative tumor growth of subcutaneous Keap1 mutant (e) or wildtype (f) tumors in animals receiving either -SG or AA CTL diet and either treated with CB-839 or vehicle. *p<0.05, **p<0.01, ****p<0.0001