Table 4.
Studies on stereotactic body radiation therapy for inoperable extrahepatic cholangiocarcinoma
| Study | Study design | No. of lesions | No. of EHCC (%) | No. of IHC (%) | Median dose, Gy | Median no. of fractions | LC at 1 y | OS at 1 y |
|---|---|---|---|---|---|---|---|---|
| Gkika et al9 | Retrospective | 43 | 26 (60%) | 17 (40%) | 45 | NR | 78% | 56% |
| Polistina et al12 | Retrospective | 10 | 10 (100%) | 0 | 30 | 3 | 80% | NR |
| Barney et al16 | Retrospective | 10 | 4 (40%) | 6 (60%) | 55 | 5 | 100% | 73% |
| Momm et al13 | Retrospective | 13 | 13 (100%) | 0 | 48 | 12 | 78% | NR |
| Mahadevan et al10 | Retrospective | 42 | 11 (26%) | 31 (74%) | 30 | 3 | 88% | 58% |
| Sandler et al6 | Retrospective | 31 | 25 (81%) | 6 (19%) | 40 | 5 | 78% | 59% |
| Jung et al11 | Retrospective | 58 | 25 (43%) | 33 (57%) | 45 | 3 | 85% | 45% |
| Kopek et al14 | Retrospective | 27 | 26 (96%) | 1 (4%) | 45 | 3 | NR | NR |
| Tao et al5 | Retrospective | 69 | 0 | 69 (100%) | 58 | 15 | 81% | 87% |
| This analysis | Retrospective | 41 | 15 (37%) | 26 (63%) | 40 | 5 | 92% | 69% |
Abbreviations: EHCC = extrahepatic cholangiocarcioma; IHC = intrahepatic cholangiocarcinoma; LC = local control; OS = overall survival.